| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Nov 5, 2006 | 27–20 | Colts +7 | Patriots +2.7 | Regular Season | |
| Nov 5, 2006 | 25–32 | Chargers +7 | Chargers +12.1 | Regular Season | |
| Nov 5, 2006 | 31–20 | Broncos +11 | Steelers +1.9 | Regular Season | |
| Nov 5, 2006 | 3–9 | 49ers +6 | Vikings +5.0 | Regular Season | |
| Nov 5, 2006 | 14–30 | Lions +16 | Falcons +4.5 | Regular Season | |
| Nov 5, 2006 | 7–37 | Jaguars +30 | Jaguars +10.1 | Regular Season | |
| Nov 5, 2006 | 20–26 | Ravens +6 | Ravens +2.7 | Regular Season | |
| Nov 5, 2006 | 10–24 | Bills +14 | Bills +2.7 | Regular Season | |
| Nov 5, 2006 | 31–13 | Dolphins +18 | Bears +10.6 | Regular Season | |
| Nov 5, 2006 | 19–22 | Commanders +3 | Commanders +2.1 | Regular Season | |
| Nov 5, 2006 | 10–14 | Giants +4 | Giants +13.1 | Regular Season | |
| Nov 5, 2006 | 31–17 | Chiefs +14 | Chiefs +2.3 | Regular Season | |
| Nov 5, 2006 | 31–14 | Saints +17 | Buccaneers +3.6 | Regular Season |