| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Oct 29, 2006 | 35–14 | Cowboys +21 | Panthers +6.9 | Regular Season | |
| Oct 29, 2006 | 13–20 | Browns +7 | Jets +0.6 | Regular Season | |
| Oct 29, 2006 | 34–31 | Colts +3 | Broncos +2.2 | Regular Season | |
| Oct 29, 2006 | 13–20 | Raiders +7 | Steelers +6.7 | Regular Season | |
| Oct 29, 2006 | 24–38 | Chargers +14 | Chargers +9.1 | Regular Season | |
| Oct 29, 2006 | 13–6 | Jaguars +7 | Eagles +2.1 | Regular Season | |
| Oct 29, 2006 | 35–22 | Ravens +13 | Saints +1.0 | Regular Season | |
| Oct 29, 2006 | 3–17 | Giants +14 | Giants +7.9 | Regular Season | |
| Oct 29, 2006 | 10–41 | Bears +31 | Bears +13.9 | Regular Season | |
| Oct 29, 2006 | 14–31 | Packers +17 | Packers +5.3 | Regular Season | |
| Oct 29, 2006 | 29–27 | Falcons +2 | Bengals +5.7 | Regular Season | |
| Oct 29, 2006 | 22–28 | Titans +6 | Titans +2.7 | Regular Season | |
| Oct 29, 2006 | 28–35 | Chiefs +7 | Chiefs +2.6 | Regular Season |