| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Sep 17, 2006 | 10–27 | Cowboys +17 | Cowboys +0.7 | Regular Season | |
| Sep 17, 2006 | 6–9 | Broncos +3 | Broncos +5.6 | Regular Season | |
| Sep 17, 2006 | 7–40 | Chargers +33 | Chargers +11.4 | Regular Season | |
| Sep 17, 2006 | 24–17 | Patriots +7 | Patriots +4.4 | Regular Season | |
| Sep 17, 2006 | 10–21 | Seahawks +11 | Seahawks +10.9 | Regular Season | |
| Sep 17, 2006 | 13–20 | 49ers +7 | Rams +2.4 | Regular Season | |
| Sep 17, 2006 | 3–14 | Falcons +11 | Falcons +4.7 | Regular Season | |
| Sep 17, 2006 | 16–6 | Bills +10 | Dolphins +4.3 | Regular Season | |
| Sep 17, 2006 | 13–16 | Vikings +3 | Vikings +2.0 | Regular Season | |
| Sep 17, 2006 | 7–34 | Bears +27 | Bears +9.0 | Regular Season | |
| Sep 17, 2006 | 17–34 | Bengals +17 | Bengals +9.6 | Regular Season | |
| Sep 17, 2006 | 24–43 | Colts +19 | Colts +16.6 | Regular Season | |
| Sep 17, 2006 | 6–28 | Ravens +22 | Ravens +8.9 | Regular Season | |
| Sep 17, 2006 | 34–27 | Saints +7 | Packers +3.5 | Regular Season | |
| Sep 17, 2006 | 30–24 | Giants +6 | Eagles +2.7 | Regular Season |