| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Oct 9, 2005 | 20–23 | Jaguars +3 | Bengals +0.3 | Regular Season | |
| Oct 9, 2005 | 24–20 | Panthers +4 | Panthers +4.4 | Regular Season | |
| Oct 9, 2005 | 10–33 | Cowboys +23 | Eagles +4.7 | Regular Season | |
| Oct 9, 2005 | 19–21 | Broncos +2 | Broncos +7.9 | Regular Season | |
| Oct 9, 2005 | 28–3 | Colts +25 | Colts +8.1 | Regular Season | |
| Oct 9, 2005 | 31–28 | Patriots +3 | Patriots +2.3 | Regular Season | |
| Oct 9, 2005 | 10–20 | Browns +10 | Browns +2.7 | Regular Season | |
| Oct 9, 2005 | 12–14 | Jets +2 | Jets +2.3 | Regular Season | |
| Oct 9, 2005 | 17–35 | Lions +18 | Ravens +2.4 | Regular Season | |
| Oct 9, 2005 | 14–20 | Bills +6 | Bills +4.3 | Regular Season | |
| Oct 9, 2005 | 3–52 | Packers +49 | Packers +4.4 | Regular Season | |
| Oct 9, 2005 | 34–20 | Titans +14 | Texans +2.2 | Regular Season | |
| Oct 9, 2005 | 37–31 | Seahawks +6 | Rams +2.7 | Regular Season |