| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Sep 22, 2000 | 7–1 | Diamondbacks +6 | Giants +0.7 | Regular Season | |
| Sep 22, 2000 | 3–2 | Padres +1 | Dodgers +0.4 | Regular Season | |
| Sep 22, 2000 | 8–3 | Athletics +5 | Mariners +0.2 | Regular Season | |
| Sep 22, 2000 | 8–4 | Marlins +4 | Rockies +0.6 | Regular Season | |
| Sep 22, 2000 | 5–4 | White Sox +1 | White Sox +0.7 | Regular Season | |
| Sep 22, 2000 | 2–3 | Royals +1 | Guardians +0.7 | Regular Season | |
| Sep 22, 2000 | 2–1 | Angels +1 | Rangers +0.3 | Regular Season | |
| Sep 22, 2000 | 4–6 | Nationals +2 | Braves +1.0 | Regular Season | |
| Sep 22, 2000 | 3–1 | Orioles +2 | Red Sox +0.8 | Regular Season | |
| Sep 22, 2000 | 5–12 | Reds +7 | Reds +0.3 | Regular Season | |
| Sep 22, 2000 | 9–6 | Tigers +3 | Yankees +1.3 | Regular Season | |
| Sep 22, 2000 | 9–6 | Mets +3 | Mets +0.8 | Regular Season | |
| Sep 22, 2000 | 3–2 | Rays +1 | Blue Jays +1.2 | Regular Season | |
| Sep 22, 2000 | 4–5 | Cubs +1 | Cardinals +0.8 | Regular Season |