| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Sep 21, 2000 | 7–8 | Giants +1 | Giants +0.6 | Regular Season | |
| Sep 21, 2000 | 5–2 | Athletics +3 | Mariners +0.3 | Regular Season | |
| Sep 21, 2000 | 9–4 | White Sox +5 | White Sox +0.7 | Regular Season | |
| Sep 21, 2000 | 3–8 | Royals +5 | Angels +0.2 | Regular Season | |
| Sep 21, 2000 | 2–12 | Brewers +10 | Brewers +0.4 | Regular Season | |
| Sep 21, 2000 | 8–5 | Guardians +3 | Red Sox +0.1 | Regular Season | |
| Sep 21, 2000 | 5–6 | Phillies +1 | Mets +0.8 | Regular Season | |
| Sep 21, 2000 | 1–3 | Blue Jays +2 | Yankees +0.4 | Regular Season | |
| Sep 21, 2000 | 4–13 | Rockies +9 | Rockies +0.1 | Regular Season | |
| Sep 21, 2000 | 3–10 | Nationals +7 | Nationals +0.1 | Regular Season | |
| Sep 21, 2000 | 7–5 | Astros +2 | Cardinals +0.4 | Regular Season | |
| Sep 21, 2000 | 8–9 | Red Sox +1 | Red Sox +0.0 | Regular Season |