| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Dec 26, 2021 | 14–56 | Cowboys +42 | Cowboys +8.3 | Regular Season | |
| Dec 26, 2021 | 13–17 | Raiders +4 | Raiders +2.7 | Regular Season | |
| Dec 26, 2021 | 10–36 | Chiefs +26 | Chiefs +10.3 | Regular Season | |
| Dec 26, 2021 | 25–24 | Bears +1 | Seahawks +7.9 | Regular Season | |
| Dec 26, 2021 | 16–20 | Falcons +4 | Falcons +7.3 | Regular Season | |
| Dec 26, 2021 | 21–41 | Bengals +20 | Ravens +1.8 | Regular Season | |
| Dec 26, 2021 | 33–21 | Bills +12 | Patriots +2.4 | Regular Season | |
| Dec 26, 2021 | 32–6 | Buccaneers +26 | Buccaneers +7.4 | Regular Season | |
| Dec 26, 2021 | 29–41 | Texans +12 | Chargers +4.1 | Regular Season | |
| Dec 26, 2021 | 21–26 | Jets +5 | Jets +5.0 | Regular Season | |
| Dec 26, 2021 | 30–23 | Rams +7 | Rams +0.3 | Regular Season | |
| Dec 26, 2021 | 10–34 | Eagles +24 | Eagles +8.1 | Regular Season |