| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Dec 19, 2021 | 9–0 | Saints +9 | Buccaneers +8.0 | Regular Season | |
| Dec 19, 2021 | 13–31 | 49ers +18 | 49ers +7.4 | Regular Season | |
| Dec 19, 2021 | 15–10 | Bengals +5 | Broncos +3.0 | Regular Season | |
| Dec 19, 2021 | 12–30 | Lions +18 | Cardinals +8.7 | Regular Season | |
| Dec 19, 2021 | 31–30 | Packers +1 | Packers +0.4 | Regular Season | |
| Dec 19, 2021 | 14–31 | Bills +17 | Bills +12.1 | Regular Season | |
| Dec 19, 2021 | 21–6 | Cowboys +15 | Cowboys +4.4 | Regular Season | |
| Dec 19, 2021 | 30–16 | Texans +14 | Texans +0.1 | Regular Season | |
| Dec 19, 2021 | 24–31 | Dolphins +7 | Dolphins +11.5 | Regular Season | |
| Dec 19, 2021 | 13–19 | Steelers +6 | Titans +1.5 | Regular Season |