| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Dec 5, 2010 | 13–10 | Steelers +3 | Ravens +3.9 | Regular Season | |
| Dec 5, 2010 | 28–24 | Falcons +4 | Falcons +2.2 | Regular Season | |
| Dec 5, 2010 | 14–31 | Seahawks +17 | Seahawks +4.6 | Regular Season | |
| Dec 5, 2010 | 19–6 | Rams +13 | Cardinals +5.5 | Regular Season | |
| Dec 5, 2010 | 38–35 | Cowboys +3 | Colts +7.5 | Regular Season | |
| Dec 5, 2010 | 28–13 | Raiders +15 | Chargers +11.9 | Regular Season | |
| Dec 5, 2010 | 14–38 | Vikings +24 | Vikings +7.9 | Regular Season | |
| Dec 5, 2010 | 24–20 | Bears +4 | Bears +7.4 | Regular Season | |
| Dec 5, 2010 | 34–30 | Saints +4 | Saints +7.2 | Regular Season | |
| Dec 5, 2010 | 6–10 | Chiefs +4 | Chiefs +5.0 | Regular Season | |
| Dec 5, 2010 | 17–6 | Jaguars +11 | Titans +5.7 | Regular Season | |
| Dec 5, 2010 | 13–10 | Browns +3 | Dolphins +5.1 | Regular Season | |
| Dec 5, 2010 | 16–34 | Packers +18 | Packers +10.4 | Regular Season | |
| Dec 5, 2010 | 7–31 | Giants +24 | Giants +8.3 | Regular Season |