| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Nov 28, 2010 | 36–14 | Chargers +22 | Colts +5.2 | Regular Season | |
| Nov 28, 2010 | 36–33 | Rams +3 | Broncos +6.3 | Regular Season | |
| Nov 28, 2010 | 10–17 | Ravens +7 | Ravens +8.2 | Regular Season | |
| Nov 28, 2010 | 26–31 | Bears +5 | Eagles +0.3 | Regular Season | |
| Nov 28, 2010 | 42–24 | Chiefs +18 | Seahawks +2.7 | Regular Season | |
| Nov 28, 2010 | 33–17 | Dolphins +16 | Raiders +1.0 | Regular Season | |
| Nov 28, 2010 | 23–24 | Browns +1 | Browns +5.7 | Regular Season | |
| Nov 28, 2010 | 17–20 | Falcons +3 | Falcons +2.1 | Regular Season | |
| Nov 28, 2010 | 19–16 | Steelers +3 | Steelers +5.5 | Regular Season | |
| Nov 28, 2010 | 0–20 | Texans +20 | Titans +0.3 | Regular Season | |
| Nov 28, 2010 | 20–24 | Giants +4 | Giants +5.1 | Regular Season | |
| Nov 28, 2010 | 17–13 | Vikings +4 | Vikings +0.3 | Regular Season |