| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Nov 14, 2010 | 39–26 | Patriots +13 | Steelers +4.3 | Regular Season | |
| Nov 14, 2010 | 36–18 | Seahawks +18 | Cardinals +5.8 | Regular Season | |
| Nov 14, 2010 | 33–20 | Cowboys +13 | Giants +7.9 | Regular Season | |
| Nov 14, 2010 | 20–23 | 49ers +3 | 49ers +6.7 | Regular Season | |
| Nov 14, 2010 | 29–49 | Broncos +20 | Broncos +2.0 | Regular Season | |
| Nov 14, 2010 | 24–31 | Jaguars +7 | Jaguars +1.9 | Regular Season | |
| Nov 14, 2010 | 12–14 | Bills +2 | Bills +5.5 | Regular Season | |
| Nov 14, 2010 | 16–31 | Buccaneers +15 | Buccaneers +3.6 | Regular Season | |
| Nov 14, 2010 | 13–27 | Bears +14 | Bears +2.0 | Regular Season | |
| Nov 14, 2010 | 17–23 | Colts +6 | Colts +10.7 | Regular Season | |
| Nov 14, 2010 | 26–20 | Jets +6 | Jets +4.3 | Regular Season | |
| Nov 14, 2010 | 17–29 | Dolphins +12 | Titans +1.5 | Regular Season |