| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Oct 31, 2010 | 10–20 | Saints +10 | Saints +2.3 | Regular Season | |
| Oct 31, 2010 | 38–35 | Buccaneers +3 | Cardinals +5.5 | Regular Season | |
| Oct 31, 2010 | 3–33 | Raiders +30 | Raiders +2.0 | Regular Season | |
| Oct 31, 2010 | 18–28 | Patriots +10 | Patriots +6.1 | Regular Season | |
| Oct 31, 2010 | 25–33 | Chargers +8 | Chargers +1.2 | Regular Season | |
| Oct 31, 2010 | 10–13 | Chiefs +3 | Chiefs +5.6 | Regular Season | |
| Oct 31, 2010 | 24–16 | 49ers +8 | 49ers +1.8 | Regular Season | |
| Oct 31, 2010 | 22–14 | Dolphins +8 | Bengals +2.7 | Regular Season | |
| Oct 31, 2010 | 35–17 | Jaguars +18 | Cowboys +8.0 | Regular Season | |
| Oct 31, 2010 | 9–0 | Packers +9 | Jets +5.0 | Regular Season | |
| Oct 31, 2010 | 25–37 | Lions +12 | Commanders +4.4 | Regular Season | |
| Oct 31, 2010 | 10–20 | Rams +10 | Panthers +2.2 | Regular Season |