| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Oct 17, 2010 | 27–24 | Colts +3 | Colts +4.4 | Regular Season | |
| Oct 17, 2010 | 21–24 | Vikings +3 | Vikings +2.7 | Regular Season | |
| Oct 17, 2010 | 24–20 | Jets +4 | Jets +4.3 | Regular Season | |
| Oct 17, 2010 | 9–17 | 49ers +8 | 49ers +3.5 | Regular Season | |
| Oct 17, 2010 | 20–28 | Giants +8 | Giants +13.1 | Regular Season | |
| Oct 17, 2010 | 31–35 | Texans +4 | Texans +7.1 | Regular Season | |
| Oct 17, 2010 | 17–31 | Eagles +14 | Eagles +2.7 | Regular Season | |
| Oct 17, 2010 | 20–23 | Patriots +3 | Patriots +3.1 | Regular Season | |
| Oct 17, 2010 | 23–20 | Seahawks +3 | Bears +8.1 | Regular Season | |
| Oct 17, 2010 | 10–28 | Steelers +18 | Steelers +12.2 | Regular Season | |
| Oct 17, 2010 | 23–20 | Dolphins +3 | Packers +7.9 | Regular Season | |
| Oct 17, 2010 | 31–6 | Saints +25 | Saints +4.2 | Regular Season | |
| Oct 17, 2010 | 17–20 | Rams +3 | Chargers +7.2 | Regular Season |