| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Sep 12, 2010 | 7–13 | Commanders +6 | Cowboys +4.2 | Regular Season | |
| Sep 12, 2010 | 27–20 | Packers +7 | Eagles +4.2 | Regular Season | |
| Sep 12, 2010 | 6–31 | Seahawks +25 | 49ers +0.3 | Regular Season | |
| Sep 12, 2010 | 17–13 | Cardinals +4 | Cardinals +6.9 | Regular Season | |
| Sep 12, 2010 | 18–31 | Giants +13 | Giants +2.0 | Regular Season | |
| Sep 12, 2010 | 17–24 | Jaguars +7 | Jaguars +2.1 | Regular Season | |
| Sep 12, 2010 | 9–15 | Steelers +6 | Steelers +5.7 | Regular Season | |
| Sep 12, 2010 | 15–10 | Dolphins +5 | Bills +2.7 | Regular Season | |
| Sep 12, 2010 | 14–19 | Bears +5 | Bears +10.4 | Regular Season | |
| Sep 12, 2010 | 24–38 | Patriots +14 | Patriots +7.6 | Regular Season | |
| Sep 12, 2010 | 14–17 | Buccaneers +3 | Buccaneers +2.7 | Regular Season | |
| Sep 12, 2010 | 24–34 | Texans +10 | Colts +1.5 | Regular Season | |
| Sep 12, 2010 | 13–38 | Titans +25 | Titans +10.1 | Regular Season |