| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Oct 22, 2000 | 35–16 | Commanders +19 | Jaguars +2.1 | Regular Season | |
| Oct 22, 2000 | 0–22 | Steelers +22 | Steelers +10.0 | Regular Season | |
| Oct 22, 2000 | 3–31 | Raiders +28 | Raiders +7.9 | Regular Season | |
| Oct 22, 2000 | 21–19 | Saints +2 | Falcons +4.6 | Regular Season | |
| Oct 22, 2000 | 9–13 | Eagles +4 | Eagles +8.2 | Regular Season | |
| Oct 22, 2000 | 14–6 | Titans +8 | Titans +2.2 | Regular Season | |
| Oct 22, 2000 | 27–31 | Vikings +4 | Vikings +8.1 | Regular Season | |
| Oct 22, 2000 | 16–34 | Panthers +18 | Panthers +5.0 | Regular Season | |
| Oct 22, 2000 | 7–48 | Cowboys +41 | Cowboys +7.0 | Regular Season | |
| Oct 22, 2000 | 21–31 | Bengals +10 | Broncos +7.7 | Regular Season | |
| Oct 22, 2000 | 23–30 | Colts +7 | Colts +6.6 | Regular Season | |
| Oct 22, 2000 | 34–54 | Chiefs +20 | Rams +2.6 | Regular Season |