| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Oct 8, 2000 | 15–10 | Ravens +5 | Jaguars +4.3 | Regular Season | |
| Oct 8, 2000 | 21–29 | Cardinals +8 | Cardinals +3.5 | Regular Season | |
| Oct 8, 2000 | 3–26 | Panthers +23 | Panthers +2.0 | Regular Season | |
| Oct 8, 2000 | 21–7 | Broncos +14 | Broncos +4.2 | Regular Season | |
| Oct 8, 2000 | 13–6 | Giants +7 | Falcons +2.1 | Regular Season | |
| Oct 8, 2000 | 34–28 | Raiders +6 | Raiders +2.3 | Regular Season | |
| Oct 8, 2000 | 31–10 | Saints +21 | Bears +5.3 | Regular Season | |
| Oct 8, 2000 | 13–22 | Dolphins +9 | Dolphins +2.7 | Regular Season | |
| Oct 8, 2000 | 16–24 | Patriots +8 | Colts +0.3 | Regular Season | |
| Oct 8, 2000 | 17–14 | Commanders +3 | Commanders +0.3 | Regular Season | |
| Oct 8, 2000 | 24–31 | Lions +7 | Lions +0.2 | Regular Season | |
| Oct 8, 2000 | 20–3 | Steelers +17 | Jets +9.9 | Regular Season | |
| Oct 8, 2000 | 23–14 | Titans +9 | Titans +9.0 | Regular Season |