| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Oct 1, 2000 | 10–38 | Eagles +28 | Eagles +2.2 | Regular Season | |
| Oct 1, 2000 | 20–27 | 49ers +7 | 49ers +4.4 | Regular Season | |
| Oct 1, 2000 | 27–24 | Bears +3 | Packers +10.3 | Regular Season | |
| Oct 1, 2000 | 17–20 | Commanders +3 | Buccaneers +0.3 | Regular Season | |
| Oct 1, 2000 | 28–19 | Patriots +9 | Broncos +8.2 | Regular Season | |
| Oct 1, 2000 | 31–16 | Dolphins +15 | Dolphins +6.6 | Regular Season | |
| Oct 1, 2000 | 12–0 | Ravens +12 | Ravens +4.3 | Regular Season | |
| Oct 1, 2000 | 24–13 | Steelers +11 | Jaguars +10.0 | Regular Season | |
| Oct 1, 2000 | 14–28 | Titans +14 | Titans +8.2 | Regular Season | |
| Oct 1, 2000 | 16–13 | Cowboys +3 | Panthers +4.3 | Regular Season | |
| Oct 1, 2000 | 31–57 | Rams +26 | Rams +13.6 | Regular Season | |
| Oct 1, 2000 | 18–16 | Colts +2 | Bills +4.0 | Regular Season | |
| Oct 1, 2000 | 31–24 | Vikings +7 | Vikings +4.4 | Regular Season |