| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Sep 24, 2000 | 16–6 | Commanders +10 | Giants +2.9 | Regular Season | |
| Sep 24, 2000 | 10–36 | Raiders +26 | Raiders +9.4 | Regular Season | |
| Sep 24, 2000 | 23–22 | Chiefs +1 | Broncos +5.1 | Regular Season | |
| Sep 24, 2000 | 20–12 | Seahawks +8 | Seahawks +0.3 | Regular Season | |
| Sep 24, 2000 | 21–17 | Jets +4 | Buccaneers +4.6 | Regular Season | |
| Sep 24, 2000 | 29–3 | Packers +26 | Packers +2.4 | Regular Season | |
| Sep 24, 2000 | 41–24 | 49ers +17 | Cowboys +7.9 | Regular Season | |
| Sep 24, 2000 | 3–10 | Dolphins +7 | Dolphins +5.1 | Regular Season | |
| Sep 24, 2000 | 41–20 | Rams +21 | Rams +4.4 | Regular Season | |
| Sep 24, 2000 | 0–37 | Ravens +37 | Ravens +10.3 | Regular Season | |
| Sep 24, 2000 | 21–14 | Lions +7 | Lions +0.3 | Regular Season | |
| Sep 24, 2000 | 21–7 | Eagles +14 | Saints +1.7 | Regular Season | |
| Sep 24, 2000 | 23–20 | Titans +3 | Titans +4.3 | Regular Season |