| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Sep 17, 2000 | 6–19 | Dolphins +13 | Dolphins +2.7 | Regular Season | |
| Sep 17, 2000 | 21–13 | Vikings +8 | Vikings +3.1 | Regular Season | |
| Sep 17, 2000 | 10–20 | Seahawks +10 | Seahawks +8.0 | Regular Season | |
| Sep 17, 2000 | 33–24 | Broncos +9 | Raiders +2.1 | Regular Season | |
| Sep 17, 2000 | 10–42 | Chiefs +32 | Chiefs +5.2 | Regular Season | |
| Sep 17, 2000 | 14–7 | Giants +7 | Giants +1.3 | Regular Season | |
| Sep 17, 2000 | 31–10 | Buccaneers +21 | Buccaneers +2.2 | Regular Season | |
| Sep 17, 2000 | 14–27 | Jets +13 | Jets +2.7 | Regular Season | |
| Sep 17, 2000 | 15–10 | Falcons +5 | Panthers +4.4 | Regular Season | |
| Sep 17, 2000 | 0–13 | Jaguars +13 | Jaguars +14.7 | Regular Season | |
| Sep 17, 2000 | 20–23 | Browns +3 | Steelers +0.3 | Regular Season | |
| Sep 17, 2000 | 3–6 | Packers +3 | Packers +7.7 | Regular Season | |
| Sep 17, 2000 | 24–41 | Rams +17 | Rams +13.3 | Regular Season |