| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Sep 10, 2000 | 31–32 | Cardinals +1 | Cowboys +0.3 | Regular Season | |
| Sep 10, 2000 | 14–42 | Broncos +28 | Broncos +5.3 | Regular Season | |
| Sep 10, 2000 | 10–15 | Lions +5 | Commanders +0.2 | Regular Season | |
| Sep 10, 2000 | 38–22 | Panthers +16 | 49ers +1.5 | Regular Season | |
| Sep 10, 2000 | 28–27 | Saints +1 | Chargers +5.9 | Regular Season | |
| Sep 10, 2000 | 37–34 | Rams +3 | Rams +2.3 | Regular Season | |
| Sep 10, 2000 | 14–17 | Titans +3 | Titans +7.1 | Regular Season | |
| Sep 10, 2000 | 36–39 | Ravens +3 | Jaguars +2.4 | Regular Season | |
| Sep 10, 2000 | 33–18 | Giants +15 | Eagles +2.5 | Regular Season | |
| Sep 10, 2000 | 18–27 | Bills +9 | Bills +4.2 | Regular Season | |
| Sep 10, 2000 | 0–41 | Buccaneers +41 | Buccaneers +10.0 | Regular Season | |
| Sep 10, 2000 | 24–7 | Browns +17 | Bengals +3.6 | Regular Season | |
| Sep 10, 2000 | 38–31 | Raiders +7 | Colts +3.6 | Regular Season | |
| Sep 10, 2000 | 7–13 | Vikings +6 | Vikings +6.9 | Regular Season |