| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Sep 25, 2010 | 6–2 | White Sox +4 | Angels +0.4 | Regular Season | |
| Sep 25, 2010 | 2–5 | Diamondbacks +3 | Dodgers +0.4 | Regular Season | |
| Sep 25, 2010 | 9–10 | Rockies +1 | Rockies +0.2 | Regular Season | |
| Sep 25, 2010 | 4–0 | Marlins +4 | Brewers +0.0 | Regular Season | |
| Sep 25, 2010 | 1–9 | Rays +8 | Rays +1.3 | Regular Season | |
| Sep 25, 2010 | 1–7 | Guardians +6 | Guardians +0.3 | Regular Season | |
| Sep 25, 2010 | 10–11 | Tigers +1 | Twins +0.3 | Regular Season | |
| Sep 25, 2010 | 4–6 | Pirates +2 | Astros +0.8 | Regular Season | |
| Sep 25, 2010 | 5–2 | Mets +3 | Phillies +1.3 | Regular Season | |
| Sep 25, 2010 | 7–3 | Red Sox +4 | Yankees +0.5 | Regular Season | |
| Sep 25, 2010 | 3–4 | Padres +1 | Padres +0.2 | Regular Season | |
| Sep 25, 2010 | 4–3 | Rangers +1 | Rangers +0.1 | Regular Season | |
| Sep 25, 2010 | 4–5 | Blue Jays +1 | Blue Jays +0.9 | Regular Season | |
| Sep 25, 2010 | 5–0 | Braves +5 | Braves +0.7 | Regular Season | |
| Sep 25, 2010 | 3–7 | Cubs +4 | Cubs +0.0 | Regular Season |